Hepatitis C: a clinical review

Hepatitis C: a clinical review.

Hepatitis C is a major cause of chronic liver disease. It has been recognized as a global health problem because of the progression to cirrhosis and hepatocellular cancer. Chronic hepatitis C is usually asymptomatic but can cause considerable liver damage before its recognition. This review discusses the natural history, clinical features, diagnosis, therapy, treatment responses and the side ef...

Combating Hepatitis C (HCV): A Review of Present & Future Perspectives

Abstract: Over the past few decades, the race against the treatment strategies of infectious HCV has gained a lot of momentum. These treatments include several therapies like Ribavirin, INF-α, DAA based pro-drugs, vaccines, and even naturally occurring compounds like herbal extracts as well as scorpion venom. All of these drugs have their specialized techniques and methodologies of administrati...

How Hepatitis C Virus Infection Contributes to Cardiovascular Disease: A Systematic Review

Treatment of hepatitis C: a systematic review.

IMPORTANCE Hepatitis C virus (HCV) infects more than 185 million individuals worldwide. Twenty percent of patients chronically infected with HCV progress to cirrhosis. New, simpler therapeutics using direct-acting antivirals that target various stages of the HCV life cycle are in development to eradicate HCV without concomitant interferon. OBJECTIVES To summarize published evidence on safety,...

Hepatitis C: a brief clinical overview.

Hepatitis C has emerged as an important public health problem that has affected 3.9 million Americans and 170 million people worldwide and is currently the most common indication for orthotopic liver transplantation. The disease, characterized by asymptomatic onset, is often discovered incidentally through blood tests obtained during routine physical examination or before blood donation. Sponta...